![]() Gastrointestinalįrequency not reported: Glossitis, stomatitis, pseudomembranous enterocolitis, pancreatitis, emesis, abdominal pain, pseudomembranous colitis, Clostridium difficile-associated diarrhea, constipation, sore mouth Nervous systemĪseptic meningitis was rapidly reversible when this drug was stopped but recurred in several cases upon re-exposure to either this combination drug or to trimethoprim alone. Hypoglycemia has been reported in patients using sulfonamides. Postmarketing reports: Metabolic acidosis Metabolicįrequency not reported: Anorexia, hypoglycemia, hyponatremia, decreased appetite The most common side effects were gastrointestinal disturbances (nausea, vomiting, anorexia) and allergic skin reactions (e.g., rash, urticaria).Įffects associated with Pneumocystis jirovecii pneumonia management have included severe hypersensitivity reactions, rash, pyrexia, neutropenia, thrombocytopenia, elevated liver enzymes, hyperkalemia, hyponatremia, and rhabdomyolysis such effects were very rare.Īlthough rare, fatalities associated with sulfonamide use have occurred due to severe reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, other blood dyscrasias, and respiratory hypersensitivity. seeing, hearing, or feeling things that are not thereĪpplies to sulfamethoxazole / trimethoprim: intravenous solution, oral suspension, oral tablet.redness or other discoloration of the skin.muscle pain, stiffness, cramps, or spasms.increased sensitivity of the skin to sunlight.feeling of constant movement of self or surroundings.Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.Ĭheck with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common These side effects may go away during treatment as your body adjusts to the medicine. Some side effects of sulfamethoxazole / trimethoprim may occur that usually do not need medical attention. unsteadiness, trembling, or other problems with muscle control or coordination.swelling of the face, hands, legs, and feet.redness, swelling, or soreness of the tongue.raised red swellings on the skin, the buttocks, legs, or ankles.puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue.numbness or tingling in the hands, feet, or lips.large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs.large, flat, blue, or purplish patches in the skin.general feeling of discomfort or illness.fast, pounding, or irregular heartbeat or pulse.continuing ringing or buzzing or other unexplained noise in the ears.burning, crawling, itching, numbness, painful, prickling, "pins and needles", or tingling feelings.bluish-colored lips, fingernails, or palms.sores, ulcers, or white spots in the mouth or on the lips. ![]()
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